http://saurabhgombar.com Fri, 10 Jul 2015 04:02:36 +0000 hourly 1 https://wordpress.org/?v=3.9.39 http://saurabhgombar.com/clinical-use-of-engineered-cells-chimeric-antigen-receptor-t-cells/#comment-36 Fri, 10 Jul 2015 04:02:36 +0000 http://saurabhgombar.com/?p=46#comment-36 Thanks Deb! Therapies using regulatory T-cells are still in the clinical trial stage so commercial availability of highly targeted therapy will still be at least 5-10 years away. That being said there is molecule in the body called interleukin 2 (IL2) that has been shown to boost the function of regulatory T-cells. We can synthesize IL2 in the lab and it is an FDA approved drug to help treat several cancers. There are a few large trials ongoing for the use of IL2 to reduce the burden of autoimmune disorders and the early results are promising. If the large clinical trials show beneficial effect you will probably see IL2 widely available for autoimmune disorders. The current large trial is set to complete in October 2016. https://clinicaltrials.gov/ct2/show/NCT01988506?term=regulatory+cell+autoimmune&rank=5

]]> http://saurabhgombar.com/clinical-use-of-engineered-cells-chimeric-antigen-receptor-t-cells/#comment-35 Thu, 09 Jul 2015 13:08:45 +0000 http://saurabhgombar.com/?p=46#comment-35 Very interesting article. In my family we have autoimmune UC, thyroid and celiac disease. I have autoimmune thyroid. My mother at 86 has mantle cell lymphoma stemming from her celiac disease. I find your article hopeful. Do you have an idea of when it will come to market?

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